The "Nanosystem for Covid-19 DNA/Antibodies on the Spot Test" (NACOTS) revolutionizes COVID-19 diagnostics with several innovative features: 1. Electrochemical Biosensor: NACOTS's use of electrochemical techniques such as cyclic voltammetry, differential pulse voltammetry, and square wave voltammetry enables portable, efficient, and cost-effective detection of the SARS-CoV-2 virus. 2. Simultaneous DNA and Antibody Detection: NACOTS provides exhaustive COVID-19 information by detecting viral DNA and antibodies. It redefines disease detection precision by utilizing advanced biomaterials for target recognition and signal readout sensitivity. 3. Universal Applicability: NACOT's user-friendly design and intuitive interface broaden its applicability. It can be effortlessly employed by various entities, from healthcare providers in clinical settings to lab researchers. Its ability to deliver quick, reliable results makes it an essential tool in various environments. 4. Rapid Response Time: NACOTS provides results in less than five minutes, facilitating the rapid implementation of containment strategies and disease management. 5. RT-LAMP Integration and Adaptability: NACOTS employs the highly sensitive and specific RT-LAMP technique, allowing for detecting DNA or RNA templates in less than an hour. The adaptability of the RT-LAMP technique, which can be modified to identify additional pathogens or diseases, distinguishes NACOTS as a versatile instrument for broader disease control. 6. IoT Compatibility: NACOTS, as an IoT-enabled device, facilitates the collection and processing of data in real time. Through smartphone applications or custom software, this integration ensures individualized medical care and accurate reproducibility of results. 7. Ethical Compliance: The NACOTS project emphasizes strict adherence to ethical research principles throughout its development and implementation. 8. Desktop Application and Future Adaptability: The NACOTS system is accessible via a user-friendly desktop application built with Electron and Node.js. Plans for the future include creating smartphone applications, which will further improve user accessibility and convenience. 9. Contribution to Global Health: The speed, precision, and affordability of NACOTS could revolutionize the global approach to disease control. Its ability to shape effective containment strategies, improve patient treatment plans, and drive vaccine efficacy research significantly contributes to global health advancement.