The present invention relates to a new kind of medicinal value or health care function of Parkia speciosa empty pod extract, particularly in alleviating cardiac hypertrophy. In one aspect, the present invention discloses a composition comprising an extract of Parkia speciosa empty pod for use in the reduction of the size of cardiomyocytes associated with cardiac hypertrophy condition, wherein the extract has a concentration ranging from 12.5 to 50.0 ?g/mL.