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Synergistic effect of Ganoderma lucidum & Clitoria ternatea extract on improvement of psoriasis using rat model.

improving skin psoriasis
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Reg. ID : 17535
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Description

The project focuses on improving skin psoriasis condition using natural ingredient and giving no side effects. As we know, skin is the largest organ by surface area in human which aids in protecting the internal tissues from microbial infection, mechanical damage, extreme temperature, and ultraviolet radiation. Psoriasis, is a skin disease that causes rash with itchy, scaly patches, most commonly on the knees, elbows and scalp. The painful condition may interfere with sleep and hard to concentrate on task at hand. It can triggers in people with genetic predisposition including infection, cuts, burns and medication. There has been concerns of the expanding bacterial resistance towards antibiotics or steroids accumulation. Many studies have been done by using various types of plants and chemicals in finding a safe alternative treatment on improving psoriasis condition. Bio active compounds are commonly found in many herbal plants but required details analysis, toxicology assays, and formulation on discovering the best concentration to optimized healing ability. Here, we have formulated a synergistic formulation using the main ingredient from clitoria ternatea extract and Ganoderma lucidum mushroom hot water extract. In this study, we have analyzed the bioactive compound of both ingredient and the toxicity concentration that is safe to be use.

Highlights

The identification of variations plants alkaloids, terpenoids, flavonoids, and tannins have been identified to obtained antibacterial effects and improve healing properties using rat model. Current rat model that has been induced with chemical to induce psoriasis skin condition showed improvement in skin quality, less swelling, and improve skin pigmentation. Innovate feature of this project is the use of natural resources which is clitoria ternatea and Ganoderma lucidum extract as main ingredient to help improve psoriasis skin condition. The product are formulated in the form of gel which is easy to apply to the effected skin area. We aim this project can be commercialized in the future due to its usefulness and safe for all ages, gender, ethnic and religion. It has the potential for commercialization since the low cost to create aquas gel with clitoria ternatea and Ganoderma extract. The product are made from natural ingredients and no added steroids making it suitable for sensitive skin. In addition, no alcohol is added to the product making it "halal" compliance and suitable to be used for Muslim. This innovation aims to provides a better health condition to patient suffering from psoriasis condition and its match with the goal of SDG 3 which is seeking and ensuring health and well-being for all, at every stages of life. The uniqueness of this product is that it does not involve any harmful chemicals starting from the extraction method until the finalized product. This will give a peace of mind to consumer that want to apply and use the product for substantial duration.

Contact Person/Inventor

Name Email Contact Phone
Safraa Sapawi safraasapawi@msu.edu.my 601112992833

Award

Award Title Award Achievement Award Year Received
Malaysian Technology Expo MTE 2023 2023

Video

Additional Document

Attachment Size
file-1711595975.pdf (197.15 KB) 197.15 KB
file-1711595975.pdf (301.55 KB) 301.55 KB
file-1711595975.pdf (345.75 KB) 345.75 KB
file-1711595975.pdf (38.41 KB) 38.41 KB

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