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A Quorum Sensing Inhibitor Biosensor, Method And Use Thereof

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Reg. ID : 16917
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Description

The present invention relates to a quorum biosensor. More particularly, the present invention relates to a biosensor for use in detecting short chain N-acyl homoserine lactone synthase inhibitor, characterized in that, the biosensor is a N-acyl homoserine lactone-producing Escherichia coli comprising an arabinose-dependent expression plasmid, its method of manufacturing and method of use thereof. The present invention provides a novel approach for development of short chain N-acyl homoserine lactone synthase inhibitor biosensor that is capable of detecting specific compounds, in particular non-antibiotic compounds, which can be used in controlling quorum sensing-mediated bacterial infection.

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Um Centre Of Innovation And Enterprise (Umcie) umcie@um.edu.my 013-2250151 / 03-79677351

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