ELECTROCHEMICAL BIOSENSOR FOR RAPID, HIGHLY SENSITIVE DETECTION OF PYOCYANIN AS BIOMARKER OF BACTERIAL PSEUDOMONAS AERUGINOSA INFECTION AND METHOD THEREOF
Potential Commercialised
violet
Reg. ID : 17198
Comments
Description
The present invention discloses an electrochemical biosensor for rapid, highly sensitive detection of pyocyanin as a biomarker of bacterial Pseudomonas aeruginosa infection, and a method thereof. The electrochemical biosensor comprises a nanocomposite selected from a group comprising a gold nanoparticle, a silver nanoparticle, a platinum nanoparticle, an indium tin oxide nanoparticle, a polymer dot, a carbon, a carbon nanotube, a carbon nanofiber, a graphene and any combinations thereof, and a biorecognition sensing material dispersed in the nanocomposite comprising a nucleic acid binding species or aptamer containing reporter molecules configured for transducing molecular recognition of pyocyanin molecules increasingly concentrated from a fluid sample deposited thereon to a differential current signal. The biorecognition sensing material selectively subjects the concentrated pyocyanin molecules to a controlled voltage waveform that oxidizes the pyocyanin molecules, resulting in a response current signal to the said controlled voltage waveform representing a concentration of the pyocyanin in the fluid sample thereof.
Contact Person/Inventor
Name | Contact Phone | |
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Pusat Pemindahan Teknologi Dan Pengkomersialan | ttc@upnm.edu.my | 03-90513099 |
MRDCS
Intellectual Property
№ | Type of IP | Registration ID |
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1 | Patent Filed | PI 2019001127 |
Award
Award Title | Award Achievement | Award Year Received |
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0 | 0 | 0 |
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