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Method of diagnosis and/ or discrimination of prostate cancer

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Reg. ID : 16599
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Huraian

The present invention provides a method of diagnosis and/or discrimination of prostate cancer in a patient, comprising the steps of: - determining the content of ITIH4 fragment peptide in urine taken from the body of the patient, and - determining the content of ITIH4 fragment peptide in serum taken from the body of the patient, and/or determining the content of ITIL fragment peptide 1 and/or ITIL fragment peptide 2 in urine taken from the body of the patient, - calculating at least one of: - serum:urinary ITIH4 peptide fragment index, being the ratio of the content of ITIH4 fragment peptide in serum and the content of ITIH4 in urine, and - urinary ITIH4:ITIL peptide fragment index, being the ratio of the content of ITIH4 in urine and the content of ITIL fragment peptide 1 and/or ITIL fragment peptide 2 in urine, - comparing said one or both peptide fragment indexes with the indexes of healthy controls and/or individuals suffering from benign prostatic hyperplasia (BPH), wherein: - when the ratio of the content of ITIH4 fragment peptide in serum to the content of ITIH4 in urine is lower than said ratio of the healthy control and/or individuals suffering from BPH, then prostate cancer is diagnosed in said patient, and/or - when the ratio of the content of ITIH4 in urine to the content of ITIL fragment peptide 1 and/or ITIL fragment peptide 2 in urine is higher than said ratio of the healthy control and/or individuals suffering from BPH, then prostate cancer is diagnosed in said patient.

Contact Person/Inventor

Name Email Contact Phone
Um Centre Of Innovation And Enterprise (Umcie) umcie@um.edu.my 013-2250151 / 03-79677351
Jaime Jacqueline A/P Jayapalan jaime_jacklyn@um.edu.my 03-79677351

Intellectual Property

Type of IP Registration ID
1 Patent Filed PI 2016700745

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