Poultry by-products are an excellent economic resource wherein chicken skin, is considered as one of the most under-utilized poultry by-products and discarded on daily basis. Considering that poultry skin contains up to 22% protein, the waste can be utilized to produce elastin, a vital ingredient which is often incorporated in the production of functional food and drinks, anti-aging cosmetics industry, pharmaceutical and regenerative medicine. We have explored different techniques to extract elastin from chicken skin waste and discovered the new and best method which is by steam extraction. The purity and quality characteristics of the resultant elastin were also proven to be comparable to that commercially available elastin from bovine neck ligament with evidence of excellent antioxidative and antihypertensive benefits. This is the first report on elastin extraction using steam extraction from poultry skin.